Associate Research Scientist

300 George Street, 8300N
New Haven, CT 06511

Phone: (203) 737-6834
Email: dhrubajyoti.chowdhury@yale.edu
Connect: LinkedIn / Google Scholar / ResearchGate / PubMed

BSc (Hons) in Zoology, Calcutta University, India
MSc in Neuroscience, National Brain Research Centre (NBRC), India
PhD in Neuroscience, Universidad de Navarra, Spain
Postdoctoral Scholar, University of California Davis

Since my undergraduate studies I have been intrigued about how molecular and cellular changes at the synapse underlie learning and memory. This early interest directed my research career towards understanding the molecular mechanisms of synaptic plasticity in health and disease starting with the study of signaling mechanisms in Angelman Syndrome, a genetic intellectual disability disorder, in the laboratory of Dr. Nihar Ranjan Jana at NBRC. Thereafter, I did my PhD with Dr. Isabel Perez-Otaño at the University of Navarra where my thesis work identified the molecular determinants of the endocytosis of synaptic NMDA-type glutamate receptors using biochemical, molecular and imaging methods in primary neuronal cultures. I continued to pursue my interests in synapse biology with a focus on glutamate receptors during my postdoctoral work with Dr. Johannes Hell at UC Davis. My work explored the role of PSD-95 palmitoylation in activity-dependent regulation of synaptic AMPA-type glutamate receptors during homeostatic synaptic scaling using molecular tools in cultured neurons. Currently in the Biederer lab I work on the activity-dependent remodeling of the synaptic cleft proteome and the dynamic roles of cell adhesion molecules at mature synapses.