Publications
Selected Research Articles
Mapping the proteome of the synaptic cleft through proximity labeling reveals new cleft proteins
Cijsouw, T., Ramsey, A.M., Lam, T.T., Carbone, B.E., Blanpied, T.A., and Biederer, T. Proteomes. Nov 2018, 6(4), 48, doi:10.3390/proteomes6040048. Read PDF »
Structural analyses of FERM domain-mediated membrane localization of FARP1
Kuo, Y.-C., He, X., Coleman, A., Chen, Y.-J., Dasari, P., Liou, J., Biederer, T., and Zhang, X. Scientific Reports. July 2018, 8:10477, doi: 10.1038/s41598-018-28692-4. Read PDF »
Reduced insulin/insulin-like growth factor receptor signaling mitigates defective dendrite morphogenesis in mutants of the ER stress sensor IRE-1
Salzberg, Y., Coleman, A., Celestrin, K., Cohen-Berkmann., M. Biederer, T., Henis-Korenblit, S., Bülow, H.E. PLoS Genetics. Jan 2017, 13:e1006579, doi: 10.1371/journal.pgen.1006579. Read PDF »
Excitatory synaptic drive and feedforward inhibition in the hippocampal CA3 circuit are regulated by SynCAM 1
Park KA, Ribic A, Laage Gaupp FM, Coman D, Huang Y, Dulla CG, Hyder F and Biederer T. Journal of Neuroscience. Jul 2016, 36:7464-75, doi: 10.1523/JNEUROSCI.0189-16.2016. Read PDF »
Topographic mapping of the synaptic cleft into adhesive nanodomains
Perez de Arce K, Schrod N, Metzbower SW, Allgeyer E, Kong GK, Tang AH, Krupp AJ, Stein V, Liu X, Bewersdorf J, Blanpied TA, Lucić V and Biederer T. Neuron. Dec 2015, 88:1165-72, doi: 10.1016/j.neuron.2015.11.011. Read PDF »
Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1
Cheadle L and Biederer T. Journal of Neuroscience. Jun 2014, 34:7999-8009, doi: 10.1523/JNEUROSCI.3950-13.2014. Read PDF »
Structural organization and function of mouse photoreceptor ribbon synapses involve the immunoglobulin protein synaptic cell adhesion molecule 1
Ribic A, Liu X, Crair MC and Biederer T. Journal of Comparative Neurology. Mar 2014, 522:900-20, doi: 10.1002/cne.23452. Read PDF »
The synaptic adhesion molecule SynCAM 1 contributes to cocaine effects on synapse structure and psychostimulant behavior
Giza JI, Jung Y, Jeffrey RA, Neugebauer NM, Picciotto MR and Biederer T. Neuropsychopharmacology. Mar 2013, 38:628-38, doi: 10.1038/npp.2012.226. Read PDF »
The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization
Cheadle L and Biederer T. Journal of Cell Biology. Dec 2012, 199:985-1001, doi: 10.1083/jcb.201205041. Read PDF »
Lateral assembly of the immunoglobulin protein SynCAM 1 controls its adhesive function and instructs synapse formation
Fogel AI, Stagi M, Perez de Arce K and Biederer T. EMBO Journal. Sep 2011, 30:4728-38, doi: 10.1038/emboj.2011.336. Read PDF »
SynCAM 1 adhesion dynamically regulates synapse number and impacts plasticity and learning
Robbins EM, Krupp AJ, Perez de Arce K, Ghosh AK, Fogel AI, Boucard A, Südhof TC, Stein V and Biederer T. Neuron. Dec 2010, 68:894-906, doi: 10.1016/j.neuron.2010.11.003. Read PDF »
N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion
Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y and Biederer T. Journal of Biological Chemistry. Nov 2010, 285:34864-74, doi: 10.1074/jbc.M110.120865. Read PDF »
SynCAM 1 participates in axo-dendritic contact assembly and shapes neuronal growth cones
Stagi M, Fogel AI and Biederer T. Proceedings of the National Academy of Sciences USA. Apr 2010, 107:7568-73, doi: 10.1073/pnas.0911798107. Read PDF »
Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions
Thomas LA, Akins MR and Biederer T. Journal of Comparative Neurology. Sep 2008, 510:47-67, doi: 10.1002/cne.21773. Read PDF »
SynCAMs organize synapses through heterophilic adhesion
Fogel AI, Akins MR, Krupp AJ, Stagi M, Stein V and Biederer T. Journal of Neuroscience. Nov 2007, 27:12516-30, doi: 10.1523/jneurosci.2739-07.2007. Read PDF »
Mixed-culture assays for analyzing neuronal synapse formation
Biederer T and Scheiffele P. Nature Protocols. Mar 2007, 2:670-6, 10.1038/nprot.2007.92. Read PDF »
SynCAM, a synaptic adhesion molecule that drives synapse assembly
Biederer T *, Sara Y, Mozhayeva M, Atasoy D, Liu X, Kavalali ET and Südhof TC *. Science. Aug 2002, 297:1525-31, doi: 10.1126/science.1072356. (*) co-corresponding authors. Read PDF »
CASK and protein 4.1 support F-actin nucleation on neurexins
Biederer T * and Südhof TC. Journal of Biological Chemistry. Dec 2001, 276:47869-76. doi:10.1074/jbc.M105287200. (*) corresponding author. Read PDF »
Mints as adaptors. Direct binding to neurexins and recruitment of munc18
Biederer T * and Südhof TC *. Journal of Biological Chemistry. Dec 2000, 275:39803-6, doi: 10.1074/jbc.C000656200. (*) co-corresponding authors. Read PDF »
Role of Cue1p in ubiquitination and degradation at the ER surface
Biederer T, Volkwein C and Sommer T. Science. Dec 1997, 278:1806-9, doi: 10.1126/science.278.5344.1806. Read PDF »
Selected Reviews and Book Chapters
Trans-cellular nano-alignment of synaptic function
Biederer, T., Kaeser, P.S. and Blanpied, T.A. Neuron. Nov 2017, 96: 680-696. Read PDF »
Synaptic cell adhesion
Missler M, Südhof TC and Biederer T. In: Synapses. Editors: TC Südhof, M Sheng, B Sabatini. Cold Spring Harbor Laboratory Press. 2012, pp. 31-48. Read PDF »
Signaling by synaptogenic molecules
Biederer T and Stagi M. Current Opinion in Neurobiology. Jun 2008, 18:261-9, doi: 10.1016/j.conb.2008.07.014. Read PDF »
Cell-cell interactions in synaptogenesis
Akins MR and Biederer T. Current Opinion Neurobiology. Feb 2006, 16:83-9, doi: 10.1016/j.conb.2006.01.009. Read PDF »
